The purpose of this project is two-fold. The first is to visualize the mode of action of a well-known carcinogen using 3D animation. The second is to explain the advantages of using genomics technologies to augment and expedite the current traditional methods of assessing the risk of such chemicals using 2D animation. The combination of these two media to integrate multiple concepts was a challenge, but after many revisions our team came to this.
This tonal storyboard is a second step after the initial pencil sketches on paper. It is used to give a sense of the desired lighting, as well as to determine the feel that each scene/shot needed to evoke.
This project has been conducted with supervision from Nick Woolridge and Michael Corrin at the Biomedical Communications program at the University of Toronto, and with Dr. Carole Yauk and Dr. Nikolai Chepelev from Health Canada. Much of the research and guidance stemmed from the following paper:
Moffat, Ivy, Nikolai Chepelev, Mirjam Luijten, Jiri Aubrecht, Albert Jr. Fornace, Sarah Labib, Julie Bourdon-Lacombe, Byron Kuo, Julie Buick, France Lemieux, Andrew Williams, Sabina Halappanavar, and Amal Malik. "Comparison of toxicogenomics and traditional approaches in human health risk assessment of benzo(a)pyrene in drinking water". Critical Reviews in Toxicology 2015 Jan;45(1):1-43. doi: 10.3109/10408444.2014.973934.